The University of Southern California’s Information Sciences Institute (USC/ISI) along with the active support and engagement of the USAF and USSF have undertaken a series of case studies focused on developing lessons learned and identifying best practices when Agile and DevSecOps methodologies are introduced into the space-based software-only acquisition environment. A major focus of this research is discovering challenges and exploring solutions to managing resources throughout the Agile/DevSecOps system development process. Such challenges include managing dependencies on external and internal systems; staff loading and specialties over the course of the program; the introduction of new capabilities; and the availability, collection and analysis of performance metrics for improved situational awareness.